Complex factors in preconditioning – a microarray gene expression perspective

Authors: Kevin Schembri, Joseph Galea, Godfrey Grech, Christian Saliba, Christian Scerri

Corresponding: Joseph Galea (

Keywords: Preconditioning, Micro array, Complex factors, Classification

Doi: 10.7423/XJENZA.2020.1.01

Preconditioning is complex, strong, evolutionary conserved cellular survival mechanism that is exhibited by different species as well as in different organs. A focused approach on microarray evaluation of preconditioning will be used to highlight the lack of clarity in investigating this complex phenomenon, exacerbated by the absence of a standardised terminology. This paper is an extensive review of the scientific literature on the investigation of preconditioning by means of a microarray approach. It dissects the design of the experiments used to investigate such phenomenon and classifies the complex factors in investigating preconditioning. It presents an attention to detail to the lexicon with a suggested classification and terminology that describes preconditioning that may help stratify and clarify research in this field.

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