The control of developmental global gene expression

Authors: Praveena Anilal, Jean Calleja Agius, Alex Felice

Corresponding: Praveena Anilal (

Keywords: C. elegans, Regulatory network, Lineage, Spatio-temporal

Doi: 10.7423/XJENZA.2020.2.02

The complex interplay of a myriad of protein factors in embryonic development
encapsulates the importance of accuracy in the control of gene expression,
regulation and physical factors including cell-environment contact. C. elegans has
an extremely similar gene interplay and hence its study has paved way a greater
understanding. This review will explore cell lineage specification, mutual regulation,
the consequences of mutations, and how gene regulatory networks utilise spatiotemporal triggers.

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