Immature High Grade Teratoma in A 17-Year-Old Lady - a case report

Authors: John Thake, Christine Zerafa, Sheriseane Diacono

Corresponding: Sheriseane Diacono (

Keywords: Ovarian neoplasms, Immature teratoma, Biomarkers, Younger women

Doi: 10.7423/XJENZA.2023.2.05

Issue: Xjenza Online Vol. 11

Immature teratomas are uncommon, malignant ovarian neoplasms that make up less than 1% of ovarian germ cell tumours. Immature teratomas are often larger and occur in younger women (in the first three decades of life).
Case summary
A 17-year-old lady was admitted to the emergency department in view of dyspnea, severe abdominal pain, abdominal distension and loss of appetite. On CTPA she had a large pelvic mass, and was referred to gynaecology. She underwent an elective right salpingo oophorectomy and cystectomy. Histology report indicated ovarian immature teratoma (high grade, grade 3) showing extensive neuroectodermal differentiation.
The incidence of immature teratoma is highest in young adults. Most patients present with early-stage disease, are managed with fertility sparing surgery and chemotherapy with an excellent prognosis. Diagnosis requires a combination of clinical, radiological and laboratory findings.

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